Discover great EU-funded Innovations
Excellent Science INNOVATION
New mechanisms of pathogenicity
SHARE:
Market Maturity: Exploring
These are innovations that are actively exploring value creation opportunities. Learn more
Market Creation Potential
This innovation was assessed by the JRC’s Market Creation Potential indicator framework as addressing the needs of existing markets and existing customers. Learn more
Women-led innovation
A woman had a leadership role in developing this innovation in at least one of the Key Innovator organisations listed below.
Go to Market needs
Needs that, if addressed, can increase the chances this innovation gets to (or closer to) the market incude:
  • Prepare for Market entry
  • Secure capital
Location of Key Innovators developing this innovation
Key Innovators
UN Sustainable Development Goals(SDG)
This innovation contributes to the following SDG(s)
SUSTAINABLE DEVELOPMENT GOAL 2
End hunger, achieve food security and improved nutrition and promote sustainable agriculture

The UN explains: "It is time to rethink how we grow, share and consume our food.

If done right, agriculture, forestry and fisheries can provide nutritious food for all and generate decent incomes, while supporting people-centred rural development and protecting the environment.

Right now, our soils, freshwater, oceans, forests and biodiversity are being rapidly degraded. Climate change is putting even more pressure on the resources we depend on, increasing risks associated with disasters such as droughts and floods. Many rural women and men can no longer make ends meet on their land, forcing them to migrate to cities in search of opportunities.

A profound change of the global food and agriculture system is needed if we are to nourish today’s 815 million hungry and the additional 2 billion people expected by 2050.

The food and agriculture sector offers key solutions for development, and is central for hunger and poverty eradication."

SUSTAINABLE DEVELOPMENT GOAL 12
Ensure sustainable consumption and production patterns

The UN explains: "Sustainable consumption and production is about promoting resource and energy efficiency, sustainable infrastructure, and providing access to basic services, green and decent jobs and a better quality of life for all. Its implementation helps to achieve overall development plans, reduce future economic, environmental and social costs, strengthen economic competitiveness and reduce poverty.

The EU-funded Research Project
This innovation was developed under the Horizon 2020 project NoPest with an end date of 31/12/2024
  • Read more about this project on CORDIS
Description of Project NoPest
Members of the oomycete phylum represent highly problematic crop pathogens and a threat for global food security. For instance, P. infestans is the agent of potato late blight, and P. viticola of grapevine downy mildew. Oomycete infections are currently controlled by frequent applications of copper-based compounds, but the massive use of these compounds leads to pollution, residual toxicity and adverse effects on human health. The discovery of innocuous and reliable alternatives to traditional inorganic fungicides remains challenging and has been set as a high priority by EU and other countries. NoPest aims to develop an environmentally friendly approach for crop protection as an alternative to conventional chemical pesticides. The strategy, inspired by medical and pharmaceutical research, relies on peptide aptamers to counteract oomycetes infections by i) identifying small peptides (linear/cyclic peptide aptamers) that inhibit vital enzymes involved in oomycete cell wall formation and cell stability; ii) optimizing aptamer efficiency through peptidomimetics designed for field applications; iii) searching, using chemo-informatics approaches, for non-peptide small molecules that mimic the activity of aptamers. These objectives will be addressed by selecting peptide aptamers from combinatorial libraries, based on their affinity and specificity for selected protein targets. Key benefits will be i) low probability to select resistant oomycete strains and no risk of co-selection of bacteria resistant to heavy metals; ii) no impact on animal and human health; iii) low environmental impact, as the approach is based on peptides that consist of natural amino-acids; iv) potential to develop additional products that confer antimicrobial resistance to any crop pathogen. Furthermore, in order to make the new molecules competitive in the pesticide market, precision farming non-invasive sensing tools will be developed, leading to reduced pesticide usage for field treatments.

Innnovation Radar's analysis of this innovation is based on data collected on 17/02/2025.
The unique id of this innovation in the European Commission's IT systems is: 19070