PROGENY targets a foundational and sustainable innovation, exploiting unique properties of designer soap films as advanced functional materials, to be used in fundamentally new type of biomimetic devices and sensors categorized as Proto-Opto-Electro-Mechanical Systems (POEMS). A common soap film is uniquely characterized by a proton conducting, flexible, semipermeable, quasi 2-D aqueous phase, which doubles as a smooth (3.2Å roughness) and low defect substrate for self-assembled surfactant monolayers on its opposite surfaces. Synthetic surfactants are aliphatic oligomer tails modified with hydrophilic head groups, and have been traditionally designed for use as detergents or colloidal stabilizers. The scope of modifying 1D molecular wires and 2D conjugated polymers, to create novel surfactants, is wide open. These electronic molecules will be designed to significantly reduce surface tension in aqueous solution, self-assemble at water-gas interfaces, and mechanically stabilize a new class of electronic soap films, allowing radical innovations in POEMS. PROGENY will consolidate an interdisciplinary team of pioneering European experts, and its seminal set of deliverables will be foundational to consequent R&D activities in POEMS. As a final demonstrator (TRL 3-4), we will deliver - Gated electron-proton hybrid transistors that can host living cells, as foundational precursors to bionic device prototypes targeted in Phase II. Within the project, new electronic surfactant molecules will be synthesized, characterized and modelled; new categories of electronic soap films will be characterized and tested; new devices will be designed and fabricated. In an environmentally responsible research effort, all new materials will be tested for eco-toxicological impact. Sustainability of POEMS technology and its socio-economic impact will be indicated by a prospective (ex-ante) life cycle assessment (LCA). PROGENY will also deliver a white paper and a basic business plan.