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INNOVATION
Genetically modified hydrogen oxidizing bacteria (eHOBs) for beta-lactoglobulin (BLG) production.
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Market Maturity: Business Ready
These are innovations that are putting concrete market-oriented ideas together and are, for example, pursuing market studies, business plans, engagements with relevant partner and end-users. Learn more
Market Creation Potential
This innovation was assessed by the JRC’s Market Creation Potential indicator framework as addressing the needs of existing markets and existing customers. Learn more
Women-led innovation
A woman had a leadership role in developing this innovation in at least one of the Key Innovator organisations listed below.
Go to Market needs
Needs that, if addressed, can increase the chances this innovation gets to (or closer to) the market incude:
  • Prepare for Market entry
  • Scale-up market opportunities
Location of Key Innovators developing this innovation
Key Innovators
UN Sustainable Development Goals(SDG)
This innovation contributes to the following SDG(s)
SUSTAINABLE DEVELOPMENT GOAL 2
End hunger, achieve food security and improved nutrition and promote sustainable agriculture

The UN explains: "It is time to rethink how we grow, share and consume our food.

If done right, agriculture, forestry and fisheries can provide nutritious food for all and generate decent incomes, while supporting people-centred rural development and protecting the environment.

Right now, our soils, freshwater, oceans, forests and biodiversity are being rapidly degraded. Climate change is putting even more pressure on the resources we depend on, increasing risks associated with disasters such as droughts and floods. Many rural women and men can no longer make ends meet on their land, forcing them to migrate to cities in search of opportunities.

A profound change of the global food and agriculture system is needed if we are to nourish today’s 815 million hungry and the additional 2 billion people expected by 2050.

The food and agriculture sector offers key solutions for development, and is central for hunger and poverty eradication."

SUSTAINABLE DEVELOPMENT GOAL 3
Ensure healthy lives and promote well-being for all at all ages

The UN explains: "Significant strides have been made in increasing life expectancy and reducing some of the common killers responsible for child and maternal mortality.

Major progress has also been made on increasing access to clean water and sanitation, reducing malaria, tuberculosis, polio and the spread of HIV/AIDS.

However, many more efforts are needed to control a wide range of diseases and address many different persistent and emerging health issues."

SUSTAINABLE DEVELOPMENT GOAL 9
Build resilient infrastructure, promote inclusive and sustainable industrialization and foster innovation

The UN explains: "Investments in infrastructure – transport, irrigation, energy and information and communication technology – are crucial to achieving sustainable development and empowering communities in many countries. It has long been recognized that growth in productivity and incomes, and improvements in health and education outcomes require investment in infrastructure."

SUSTAINABLE DEVELOPMENT GOAL 11
Make cities and human settlements inclusive, safe, resilient and sustainable

The UN explains: "The challenges cities face can be overcome in ways that allow them to continue to thrive and grow, while improving resource use and reducing pollution and poverty. The future we want includes cities of opportunities for all, with access to basic services, energy, housing, transportation and more."

SUSTAINABLE DEVELOPMENT GOAL 12
Ensure sustainable consumption and production patterns

The UN explains: "Sustainable consumption and production is about promoting resource and energy efficiency, sustainable infrastructure, and providing access to basic services, green and decent jobs and a better quality of life for all. Its implementation helps to achieve overall development plans, reduce future economic, environmental and social costs, strengthen economic competitiveness and reduce poverty.

SUSTAINABLE DEVELOPMENT GOAL 13
Take urgent action to combat climate change and its impacts

The UN explains: "Affordable, scalable solutions are now available to enable countries to leapfrog to cleaner, more resilient economies. The pace of change is quickening as more people are turning to renewable energy and a range of other measures that will reduce emissions and increase adaptation efforts."

SUSTAINABLE DEVELOPMENT GOAL 15
Protect, restore and promote sustainable use of terrestrial ecosystems, sustainably manage forests, combat deertification, and halt and reverse land degradation and halt biodiversity loss

The UN explains: "Forests cover 30 per cent of the Earth’s surface and in addition to providing food security and shelter, forests are key to combating climate change, protecting biodiversity and the homes of the indigenous population. Thirteen million hectares of forests are being lost every year while the persistent degradation of drylands has led to the desertification of 3.6 billion hectares."

The EU-funded Research Project
This innovation was developed under the Horizon Europe project HYDROCOW with an end date of 31/08/2027
  • Read more about this project on CORDIS
Description of Project HYDROCOW
Milk protein plays an important role in our nutrition, however classical milk production has significant environmental impacts, from greenhouse gas (GHG) emissions to extensive land demand. Project HYDROCOW addresses these challenges through a net-zero carbon dairy protein production platform. The main objective of the project isto develop and demonstrate a bacterial protein secretion system where CO2 and soon N2 is valorised into food-grade protein, decoupled from agriculture. This system will base on the first-of-a-kind engineered hydrogen oxidizing bacterium (eHOB) Xanthobacter sp. SoF1. As a first product the main milk component beta-lactoglobulin was chosen. Technically this will be achieved by implementing a Design-Build-Test-Learn (DBTL) cycle linked to a validation and scale-up phase allowing to iteratively optimize the production of secreted protein. The project will deliver key technologies – A) an innovative eHOB protein secretion system; B) predictive eHOB metabolic models, genetic engineering tools, and a novel high-throughput (HTP) screening system for DBTL cycling; and C) the methods for validation and scale-up – with immediate and long-term impact on the production of food and nutrition, materials, medicines, fuels and chemicals. In the long-term, the proposed platform has the potential to not only replace conventionally produced food proteins but also deliver proteins for materials or therapeutics, important for human and animal health. In comparison to current standard microbial production processes our platform does not compete with human nutrition for valuable feedstock, such as glucose, and therefore will contribute to a sustainable development of our society. HYDROCOW will generate significant knowledge for a growing research and application community about autotrophic, microbial production systems, their physiology, and sophisticated tools for genetically designing and screening them.

Innnovation Radar's analysis of this innovation is based on data collected on 04/12/2024.
The unique id of this innovation in the European Commission's IT systems is: 131641